Glandular Odontogenic Cyst Mimicking Dentigerous Cyst: A Rare Case Report

Background: Glandular odontogenic cyst is an uncommon developmental cyst of odontogenic origin. Till now, around 200 cases have been reported in the English literature, out of which approximately 25 of them are associated with an unerupted tooth. Herein we present a case report of a 7-year-old boy with swelling in the anterior maxillary region which was later diag- nosed as a Glandular odontogenic cyst that mimicked a Dentigerous cyst. Case presentation: A painless swelling was noted in the anterior palatal region. Orthopantamogram was advised which re- vealed a unilocular radiolucency associated with an impacted supernumerary tooth. Provisional diagnosis of Dentigerous cyst was made. The cyst was enucleated in conjunction with peripheral osteotomy. The histopathological examination revealed a cystic capsule with non-keratinized stratified squamous epithelium with 2-4 cell layer thickness, with some areas showing epithelial plaque, microcysts, hobnail cells and few clear cells. Contemplating all the histological features, final diagnosis of Glandular odontogenic cyst was given. Conclusions: The presented case emphasizes the importance of histopathological examination of the unusual and rarely ob- served Glandular odontogenic cyst which can be missed due to similarities with other entities. Recurrence rates being very high, follow up of the cases is imperative.

Cisto odontogênico glandular tratamento cirúrgico por marsupialização e enucleação: relato de caso / Glandular odontogenic cyst surgical treatment by marsupialization and enucleation: case report

O cisto odontogênico glandular (COG) é o cisto de desenvolvimento mais agressivo e raro dentre todos os odontogênicos, portando características epiteliais glandulares ou salivares. O presente artigo visa retratar uma abordagem mais conservadora para esta importante lesão, no sentido de minimizar a morbidade decorrente da abordagem mais radical. Paciente com 57 anos, leucoderma, assintomático e edêntulo, compareceu ao ambulatório de estomatologia com notável expansão no fundo de saco vestibular e rebordo inferior direito, com tempo indeterminado de evolução. Os exames imaginológicos revelaram uma lesão radiolúcida unilocular extensa e bem delimitada na região anterior da mandíbula. Nas condutas propedêuticas, foi realizada uma punção aspiratória positiva para líquido cístico seguido de biópsia incisional. Diante destes achados, a marsupialização foi realizada no sentido de se conseguir a redução das dimensões lesionais, seguido da enucleação com estectomia periférica após 9 meses. Nos primeiros 2 anos de proservação o paciente mantém- -se sem recidivas e em constante acompanhamento. Conclui-se que o dentista pode preferir o método conservador pela técnica de marsupialização seguida de enucleação na abordagem de extenso cisto odontogênico glandular, desde que haja colaboração do paciente nos cuidados pós-operatórios.

The glandular odontogenic cyst (GOC) is the most aggressive and rare cyst of development among all odontogenics, with glandular or salivary epithelial characteristics. This article aims to portray a more conservative approach to this important lesion, in order to minimize the morbidity resulting from the more radical approach. Patient 57 years-old, leucoderma, asymptomatic and edentulous, attended the stomatology outpatient clinic with a remarkable expansion in the vestibular bag fundus and lower right border, with indeterminate evolution time. Imaging examinations revealed an extensive and well delimited unilocular radiolucent lesion in the anterior region of the mandible. In the propaedeutic procedures, a positive aspiration puncture was performed for cystic fluid followed by incisional biopsy. In view of these findings, marsupialization was performed in order to reduce lesion dimensions, followed by enucleation with peripheral ostectomy after 9 months. In the first 2 years of proservation, the patient remains without relapses and in constant follow-up. It is concluded that the dentist may prefer the conservative method by the marsupialization technique followed by enucleation in the approach of extensive glandular odontogenic cyst, provided there is collaboration of the patient in the postoperative care.

Glandular Odontogenic Cyst of Mandible: A Case Report.

Glandular odontogenic cysts (GOCs) are a very rare developmental cyst of the jaws. GOCs are intrabony solitary or multiloculated cyst of odontogenic origin. The importance of GOCs lies in fact that they exhibit a high propensity for recurrence. Thus, the oral physicians, radiologist, and oral pathologist play a major role in the definitive diagnosis of GOCs based on distinctive cases; though they are rare. In large part, this is due to the GOCs complex and frequently non-specific histopathology. This report describes a case of GOC occurrence in posterior mandibular angle region in a 43-year-old Irani Male, which was a rare site for its occurrence.

Bilateral glandular odontogenic cyst of the maxilla: A rare case report and review of literature.

The glandular odontogenic cyst (GOC) is a recently recognized rare developmental odontogenic cyst having an aggressive behavior and accounts for 0.012 to 1.3% of all jaw cysts. In 1992, the World Health Organization recognized this cyst as glandular odontogenic cyst (GOC). Clinically, GOC usually presents as a painless, slow-growing swelling that tends to affect the anterior part of the jaws. Many authors have suggested that the cyst mainly occurs in 4th and 5th decades and presents as an expansion of jaws with or without pain or Paraesthesia. The dental professionals must be aware of the clinical significance of this lesion as the aggressive nature of the lesion has been reported and at least 25% to 55% recur following curettage. Hence the treatment of choice is excision rather than enucleation in order to obviate recurrence. Here, we report a case of bilateral GOC in the anterior region of the maxilla, in a 29-year-old male patient, which is very unusual as it is the first bilateral case to be reported in the literature.

Glandular odontogenic cyst: Report of an unusual bilateral occurrence.

Glandular odontogenic cyst (GOC) is a recently recognized rare developmental odontogenic cyst having an aggressive behavior and accounting for 0.012% to 1.3% of all jaw cysts. GOC usually presents as a painless, slow-growing swelling that tends to affect the anterior part of the jaws. It chiefly occurs in the fourth and fifth decades of life and presents as an expansion of jaws with or without pain or paresthesia. Aggressive nature of the lesion has been reported, as supported by the fact that 25 to 55% of cases recur following curettage. So far only just over 113 cases of GOC have been reported in the literature. Here, we report a case of bilateral GOC in the posterior region of the maxilla, in a 29-year-old male patient, which is unique, being the first case of bilateral GOC to be reported in the literature.

Glandular odontogenic cyst of mandible: case report

Glandular odontogenic cyst (GOC) is an intraoral cyst originated from serre remnants which has incidence of rare frequency. Only 111 cases have been reported since Gardener first introduced it in 1987. The clinical features are the following components: cortical bone thinning, locally aggressive root resorption, non-painful swelling. The following recurrences rate are 64.3% in conservative treatment, and 0% in wide excision for instance, segmental or marginal mandibulectomy. So, its prognosis is similar to that of odontogenic keratocyst and ameloblastoma. Therefore, periodic recall follow ups are essential to detect disease recurrence. Here, we will report the first case of GOC diagnosed in our department considering with references. And we share this treatment experience because these aggessive lesions may be misjudged for simple dental cyst.

Clinical and histopathologic analysis of glandular odontogenic cysts of the jaws

An Unusual Odontogenic Cyst with Diverse Histologic Features

An unusual odontogenic cyst, which was originally believed to be a clinical dentigerous cyst associated with an impacted mandibular third molar, was found histologically to demonstrate the characteristics of a glandular odontogenic cyst with para- and orthokeratinization. These histologic diversities were interpreted as a reflection of the pluripotentiality of the epithelial remnants of the mandibular third molars or dentigerous cyst epithelium. It is possible that it has the capacity to induce the formation of cysts in both squamous and glandular epithelium.

Glandular odontogenic cyst : Report of three cases

Glandular odontogenic cyst(GOC) is a rare cyst of odontogenic origin, first described in 1988 by Gardner et al. Three glandular odontogenic cysts are presented which were experienced in the Dept. of Oral and Maxillofacial surgery, Yonsei University. The clinical characteristics, radiologic and histopathologic features, and method of treatment are discussed. One occured in the anterior maxilla, others in the mandible body area. One in the anterior maxilla showed swelling and tenderness, others not. All the lesion presented radiographically unilocular radiolucent lesion. Histopathologically, those were lined by nonkeratinizing stratified squamous epithelium of varying thickness showing plaque-like or spherical thickening. Partially, eosinophilic cuboidal cells lined the intraepithelial microcysts. Also, ciliated cuboidal cells and mucinous cells were observed. The cysts were treated by enucleation.